The easiest way of getting to Knock from within Ireland is by car, alternatively you can travel by Bus (http://www.buseireann.ie). Unfortunately there is no direct route to Knock all connections are made via Charlestown. The nearest train station is Ballyhaunis, 22Km from Knock. For international travel Ireland West Airport Knock is located 22km from the center of Knock town, with direct flights available from London, Birmingham, Edinburgh, Bristol and Leeds.
By Car Hire
Car hire is available from several agencies in the airport including Alamo, Avis, Budget, Europcar and Hertz.